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The modalities of lived experiences of catastrophic changes described by Bion in psychotic patients are useful to clinically address the catastrophic changes ensuing from psychic transformations occurring during the course of ordinary psychoanalytic treatment of children, adolescents, and adults without manifest psychosis, as well as during particular external circumstances entailing breaks in treatment and/or changes of therapist. This article sets out the example of an analyst retiring from a CMPP (Psycho-Pedagogical Medical Center), and therefore subjected to several reality principles (her obligation to retire, together with her own powerlessness in setting up in the best way her therapeutic replacement who will treat her patients). Some anxious reactions to these changes—both from the patient and the analyst—are set out and the notion of anxiety regarding catastrophic changes is analyzed as a reactivation of an unrepresentable initial anxiety. Evoking different kinds of therapeutic breaks underlines the need for the therapist to be attentive both to these constraining external events and to the psychological turbulences ensuing from these events. This article also evokes the tricky and unresolved problem of the kinds of financing of therapeutic institutions, bringing an additional “realistic” constraint unable to adapt on a clinical level to these difficult situations brought by a break in treatment.