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This exploratory study uses data from a survey conducted in Burkina Faso between October and November 2020 to assess the determinants of the effects of COVID-19 on household livelihood and income and on children’s education. Results show that workers from the informal trade sector are more likely to experience a deterioration of their livelihood and income compared to farmers, while non-migrant households seem to be more affected in terms of income and livelihood than migrant households. Regarding education, poorer households report being affected by school closure measures more than richer households.