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Due to the high morbidity and mortality and limited life expectancy of dialysis patients, it is essential to implement advance care planning in order to be aware of patients’ values and care preferences, and respect their autonomy. However, advance care planning is rarely carried out, due to the difficulty of initiating end-of-life discussions, both for patients and health professionals. The use of “serious games” in the form of card games has shown promise in supporting the implementation of advance care planning. In this article, we discuss the development of an advance care planning intervention for dialysis patients using a card game (Go Wish), in the Geneva University Hospitals Nephrology division.