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Infant gastroesophageal reflux (GERD) is a well-known condition among families and pediatricians. It is also the most common feeding disorder in children under the age of 1. The presumed causes of this condition are still predominantly physiological, and the treatments are typically medical or postural. However, to what extent could the psychological factors, transmissions, projections, and defense mechanisms involved in this disorder also be considered psychosomatic? In this article, we will focus on pathological gastroesophageal reflux and its intricacies within family dynamics. The purpose of this study is not to claim that reflux is purely psychological, but rather to explore the correlations between infant reflux and family interactions. Between causes and consequences, these two aspects resonate with one another and raise questions about their significance. From a physiological approach to a psychosomatic perspective, we will examine reflux as a vector of suffering that cannot be expressed and is passed on. We will then attempt to understand the interactions between parental psychopathology, infant psychopathology, and reflux mechanisms.