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Due to a variety of melancholic manifestations transferred onto the setting, the case of Alexandra illustrates the complexity and richness of the modes of expression of absence and loss in analysis, as well as the resistance against renunciation. In the psychoanalytic work with this patient, the question arises of the right balance between withdrawal, abstinence and the act of speech aimed at symbolization, with the attendant risk of a deterioration of the psychic situation, as in the poem Le Vase Brisé [The BrokenVase] by Sully Prudhomme. The “negative” hold of the void and of the patient’s language inhibition and silence is worked on in the transference/countertransference dynamics, in particular by means of transference through reversal, with the aim of elaborating the case and the work of melancholia clinically.