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With reference to clinical work with families, we will discuss the psychopathology of everyday life, with its experiences of alienation and insecurity from which all forms of pleasure have disappeared. The current collapse of meta-frames drives individuals towards frenetic consumption with the digital technology, social networks and screens that have invaded the home, giving daily life a frenzied pace that sometimes results in exhaustion. For adults, work no longer stops when they get home, the experience of burn-out is commonplace, and children do not want to leave their screens. Z. Bauman speaks of “liquid modernity ”, which is expressed by a volatile and ephemeral dimension in all the domains of life in society, engendering a permanent sense of insecurity. The “liquid family” caught in confusion, the erasure of limits and non-differenciation, function in a melancholic mode, tinged by hatred, where the libidinal space tends to disappear from the couple’s relationship. The analytic setting offered to the “liquid family”, which is losing its references and sense of limits, is containing and supportive and helps facilitate access to differentiations (between individuals, the sexes, roles and generations). Our remarks will be illustrated by clinical fragments.