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Background: In France, there has been a growing interest in examining the determinants of positive occupational health dimensions that contribute to employees’ quality of work life. Among those dimensions, job satisfaction has drawn the attention of many scholars. However, only few validated measures are available in French, and among these we identified the Job Satisfaction Single Item (JSSI). The aim of this article is to provide further empirical validation of the Job Satisfaction Single Item. Method: This study examined the sensitivity and criterion validity of the JSSI. More precisely, we examined, on the one hand, the links between scores on JSSIand other job satisfaction scale, and as well as occupational health and motivational measures, such as perceived stress, life satisfaction, happiness, perceived given and received social support, and finally with organizational commitment. We also verified that the JSSI is a time-saving measure, compared measure compared to longer job satisfaction scales. Results: The JSSI showed appropriate sensitivity and satisfying criterion validity with both positive and negative occupational health measures. Finally, the JSSI took significantly less time to complete than measures including five items and twenty items. Conclusion: This furthered validation reaffirmed the good psychometric qualities of the JSSI. Thus JSSI appears to be an appropriate and a time-saving measure job satisfaction, and particularly when scholars aim to examine intra-individual variability.