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Introduction: In Bagneux, a working-class suburb of Paris, during the first wave of the health crisis linked to the COVID-19 pandemic, different categories of professionals were mobilized and had to change their habits to respond to the public’s needs. Purpose of research: To collect different actors’ testimonies from the social, medical, civic, prevention, and mental health sectors about their experiences during the first wave. Method: Qualitative study with individual, semi-directive interviews. Results: The results show the redefinition of missions, an adaptation at the level of work organization, a development and reinforcement of partnership links, as well as a reconfiguration of relationships with users. On a knowledge level, we can note the acquisition of scientific knowledge and technical learning. Conclusions: The links between partners, colleagues, volunteers, and inhabitants have been reinforced. Agents have learned to better know one another. New techniques have been discovered. During a particularly difficult time, the role that they usually play in terms of health promotion has become essential. This must be further supported.