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Introduction: The aim of tuberculosis treatment is to ensure a recovery without relapse and forestall the emergence of drug resistance, however, today, the tuberculosis prevention and control program is defied by TB/VIH coinfection and multidrug resistance. Purpose of research: To identify the risk factors of the tuberculosis recurrence at Kisangani is the aim of this paper. Results: The risk factors identified are: age of 65+ years (OR = 25.70 [2.9569; 223.4762], p = 0.003); New contact with a tubercular known in the family or at the service (OR=6.00 [2.3815; 15.1205], p=0.001); crowding with a tubercular unknown in the family or at the service (OR=11.18 [5.6012; 22,3257], p=0.001); working in mines (OR=4.07 [1.6149; 10.2850], p=0.003); alcoholism (OR=3.91 [1.9385; 7.9055], p=0.001). The bacteriological reconversion is high (99%) but not associated to the groups and rho=1.2e-07. Conclusion: The recurrence of tuberculosis is a problem at Kisangani due to the risk factors. It implies the reinforcement of prevention measures to stall the transmission of the disease.