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This article offers some thoughts on the epistemological perspectives linking multiprofessionality and complementarity in relation to the singular clinical practice of supporting patients suffering from chronic pain in a centre for the evaluation and treatment of pain. The author seeks to understand the “painful object” in the light of a method of “immersion work” for which the bio-psycho-social approach proves to be entirely necessary, but also a permanent challenge for the teams at the epistemological and methodological levels. The article shows the interest of departicularizing this singular clinical practice in order to think more broadly about the complex somatopsychic states in the light of the theorization of the clinical approach to the somatic and psychic thresholds of life. In counterpoint to a meta position, these reflections invite us to think about research perspectives through, and on the basis of, intersection points identified in team immersion work.