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Introduction. – Chronic kidney disease is among the major non-communicable diseases with increasing prevalence. This study aimed to estimate the prevalence of chronic kidney disease and its associated risk factors among Moroccan population sample from Sidi Bennour province. Methods. – An observational, descriptive and analytical study was conducted in an agricultural community of Morocco. A sample of 182 subjects aged 18 or older, randomly selected from the province health care centers. The information on the participants was collected using a structured questionnaire, blood samples were collected and the serum creatinine was determined. Subsequent glomerular filtration rate (eGFR) was estimated by the modification of diet in renal disease formula and the chronic kidney disease was defined by an eGFR < 60 mL/min/1.73 m2. Results. – The participants mean age was 53.58 ± 12.06 years, with a sex ratio of 0.30 and the prevalence of chronic kidney disease was 4.4%. The risk factors associated with chronic kidney disease were age, hypertension, and nephrotoxic treatment, that are significantly correlated with renal impairment (P = 0.006 for age, P = 0.008 for hypertension and P = 0.001 for nephrotoxic medication used respectively). Conclusions. – The study data show that chronic kidney disease should be of important consideration in any strategy to address non-communicable diseases and associated risk factors.