TY  - BOOK
AU  - Doghman,Imane
AU  - Malassigné,Victor
AU  - Roucaute,Louis
AU  - Azaïs,Henri
AU  - Veyer,David
AU  - Péré,Hélène
TI  - Advances in the screening and follow-up of HPV-related cervical cancer
PY  - 2026///.
							
N1  - 37
N2  - Despite the availability of effective prevention strategies, cervical cancer (CC) remains a major global public health challenge. Persistent infection with high-risk human papillomavirus (HR-HPV) is an essential etiological factor in CC, providing an opportunity for screening and monitoring based on specific virological biomarkers. This review summarizes the current evidence on HPV-associated biomarkers in precancerous cervical lesions and cervical cancer, focusing on their role in screening, risk stratification, and patient follow-up. It traces the evolution of screening strategies, from cytology to primary HR-HPV molecular testing and the development of effective triage approaches. Next-generation sequencing technologies have enabled the detailed characterization of HPV genomic integration, highlighting its potential as a diagnostic, prognostic, and predictive biomarker. Additionally, the detection of circulating tumor HPV DNA shows significant promise for refining risk stratification and supporting non-invasive follow-up strategies. Integrating these advanced tools could lead to more efficient triage, personalized therapeutic decision-making, and optimized post-therapeutic monitoring
UR  - https://stm.cairn.info/journal-virologie-2026-1-page-7?lang=en&redirect-ssocas=7080
ER  -