Besnard, Jérémy <br/><br/>
The role of the frontal lobes in decision-making under ambiguity and under risk: Clinical, psychiatric, and neuroimaging evidence 

 -  2013.<br/>							 
<br/><br/> 12 
<br/><br/> Decision-making is a complex human activity that uses a set of cognitive and emotional processes linked to the integrity of prefrontal cortex. This paper reviews what we currently know about the link between decision-making and frontal symptomatology. Also discussed are the results of neuroimaging studies of decision-making. More precisely, the impact of focal frontal lobe lesions, obsessive-compulsive disorder, and schizophrenia on decision-making are explored. This analysis showed inhomogeneous results, both for neurological and psychiatric studies. This calls for further investigation of decision-making skills, which will be necessary to compare patients’ performance in decision-making tasks and functional outcomes, in order to explore the ecological validity of the assessment tools.