Wuestenberghs, Fabien <br/><br/>
Functional dyspepsia: What’s new in pathophysiology, and how should we diagnose and manage it? 

 -  2023.<br/>							 
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<br/><br/> Functional dyspepsia is a disorder of gut–brain interactions defined by symptoms attributed to the gastroduodenal region. Its prevalence in France is estimated at 8.5% (against 5.0% for irritable bowel syndrome, considered the prototype of functional gastrointestinal disorders). New studies have shed light on the role of the duodenum in its pathophysiology. Therapeutic management remains disappointing for most patients. First-line treatments include lifestyle and dietary modifications, proton pump inhibitors, and prokinetics. Treatment with a neuromodulator may be offered in case of failure.