TY  - BOOK
AU  - Volonté,Martina
AU  -  Codazzi,Alessia Claudia
AU  -  Davidovich,Shay
AU  -  Apicella,Antonia
AU  -  Isoletta,Eugenio
AU  -  Barruscotti,Stefania
AU  -  Massa,Margherita
AU  -  De Silvestri,Annalisa
AU  -  Marseglia,Gian Luigi
AU  -  Brazzelli,Valeria
TI  - Propranolol for the treatment of infantile hemangiomas: a nine-year monocentric experience from a tertiary hospital
PY  - 2023///.
							
N1  - 58
N2  - Background. Propranolol is currently considered the first-line therapy for problematic infantile hemangiomas (IH), the most common benign vascular neoplasm of infancy. Objectives. We present a retrospective observational study aimed at assessing the efficacy of propranolol in 44 IH patients. Materials & Methods. A nine-year retrospective review considering clinicodemographical and therapy-related variables was performed on medical records of infants treated for IH with oral propranolol. Each lesion was assessed through a numeric severity score based on size and colour both at baseline and after treatment conclusion (p Results. Complete remission was achieved in 90.7% cases of IH with a general mean improvement in severity of 94.94%. No severe adverse effects were reported. Preterm patients showed a superior response compared to term infants, even though the difference was not significant (p=0.185). Conclusion. Propranolol showed high efficacy in terms of safety profile and cosmetic results. Prematurity and precocious therapy could be linked to a superior response
UR  - https://shs.cairn.info/revue-european-journal-of-dermatology-2023-3-page-265?lang=en&redirect-ssocas=7080
ER  -