TY  - BOOK
AU  - Uozumi,Tomomi
AU  -  Serizawa,Naotaka
AU  -  Hagino,Teppei
AU  -  Morita,Takashi
AU  -  Mizuno,Maki
AU  -  Ichiyama,Susumu
AU  -  Hoashi,Toshihiko
AU  -  Saeki,Hidehisa
AU  -  Matsuda,Hiroki
AU  -  Nakagawa,Kureha
AU  -  Mitsui,Hiroshi
AU  -  Kanda,Naoko
TI  - Dietary habits in Japanese patients with bullous pemphigoid: low intake of retinol
PY  - 2023///.
							
N1  - 91
N2  - Background: Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease. Dietary habits may modulate the pathogenesis of BP. Objectives: We evaluated dietary habits in Japanese patients with BP and compared their results to those of age- and sex-matched healthy controls. We also examined the relationship between dietary habits versus IgG anti-BP180NC16A antibody or parameters of BP disease area index (BPDAI); cutaneous blisters/erosions, cutaneous urticaria/erythema, and mucosal blisters/erosions. Materials & Methods: Dietary habits were assessed by the validated, Brief-type self-administered Diet History Questionnaire. Severity of disease was assessed with BPDAI. Results: Patients with BP showed a lower intake of retinol (vitamin A1) and beverages, and a higher intake of seasoning/spices, compared to controls. The bivariate and multivariable logistic regression analysis showed that BP was associated with a low intake of retinol and beverages. There were no significant correlations between IgG anti-BP180NC16A antibody levels and intake of nutrients/foods. The BPDAI score for cutaneous blisters/erosions significantly positively correlated with intake of carbohydrate and negatively with intake of retinol, vitamin A, animal fat, cholesterol, phosphorus, and vitamin B2. The BPDAI score for cutaneous urticaria/erythema significantly negatively correlated with intake of vitamin A. BP patients with mucosal blisters/erosions had a higher intake of cholesterol, n-6 polyunsaturated fatty acid, and eggs, and lower intake of seasoning/spices, compared to patients without BP. Conclusion: The supplementation of vitamin A might have prophylactic and/or therapeutic effects on BP
UR  - https://shs.cairn.info/revue-european-journal-of-dermatology-2023-4-page-394?lang=en&redirect-ssocas=7080
ER  -