TY - BOOK AU - Maliia,Mihai Dragos AU - Philippe,Kahane AU - Nica,Anca AU - Mindruta,Ioana AU - Castana,Laura AU - Cardinale,Francesco AU - Francione,Stefano TI - SEEG re-exploration in a patient with complex frontal epilepsy with rapid perisylvian propagation and mixed “startle - reflex” seizures PY - 2021///. N1 - 6 N2 - The SEEG International Course, organised in 2017, focused on the investigation and surgery of insulo-perisylvian epilepsies. We present one representative complex case that was discussed. The patient had seizures displaying startle/reflex components. He was MRI negative, while other non-invasive investigations offered only partially concordant data. Initial SEEG exploration resulted in an incomplete definition of the epileptogenic zone. A second SEEG followed, which led to a thorough assessment of the seizure onset zone and the epileptic network, localised to the lateral inferior premotor cortex, explaining the incongruent data obtained beforehand. This was the basis of a tailored resection with a favourable outcome. The patient has been seizure-free for five years without any motor nor cognitive deficits, but with pharmacodependence to one AED. The electroclinical reasoning is presented, accompanied by relevant commentaries and recommendations from the tutors [Published with video sequences] UR - https://shs.cairn.info/revue-epileptic-disorders-2021-1-page-180?lang=en&redirect-ssocas=7080 ER -