000 02301cam a2200289zu 4500
001 88962888
003 FRCYB88962888
005 20250429180609.0
006 m o d
007 cr un
008 250429s2019 fr | o|||||0|0|||eng d
020 _a9780128164761
035 _aFRCYB88962888
040 _aFR-PaCSA
_ben
_c
_erda
100 1 _aSupuran, Claudiu T.
245 0 1 _aCarbonic Anhydrases
_bBiochemistry and Pharmacology of an Evergreen Pharmaceutical Target
_c['Supuran, Claudiu T.', 'Nocentini Ph.D., Alessio']
264 1 _bAcademic Press
_c2019
300 _a p.
336 _btxt
_2rdacontent
337 _bc
_2rdamdedia
338 _bc
_2rdacarrier
650 0 _a
700 0 _aSupuran, Claudiu T.
700 0 _aNocentini Ph.D., Alessio
856 4 0 _2Cyberlibris
_uhttps://international.scholarvox.com/netsen/book/88962888
_qtext/html
_a
520 _aCarbonic Anhydrases provides an interdisciplinary review of the burgeoning carbonic anhydrase (CA) research area, spanning from CAs classification (biochemical and structural features) to drug design and pharmacology of CA inhibitors and activators, finally touching on the biotechnological applications of these metalloenzymes. The book adopts a clear step-by-step approach and introduction to this intricate and highly interdisciplinary field. A diverse range of chapters from international experts speak to CA classification and distribution, the mechanisms of action and drug design of inhibitors and activators, the druggability of the various isoforms in the treatment of a multitude of diseases, and threats to human health. Carbonic Anhydrases provides biology, biochemistry, and medicinal chemistry students and researchers a thorough discussion and update on the evergreen and expanding research area of CAs. - Offers a full overview of CAs' biochemical and structural features, as well as drug design and pharmacology of inhibitors and activators - Provides a thorough update on the newly identified isoforms, modulating chemotypes, and innovative biomedical applications - Describes the current biotechnological applications of CAs, including processes for CO2 capture - Features chapter contributions from international leaders in CA biology, medicinal chemistry, and pharmacology
999 _c1322765
_d1322765