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001 88963922
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020 _a9780443187698
035 _aFRCYB88963922
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_ben
_c
_erda
100 1 _aPandey Phd, Rajesh
245 0 1 _aGenomic Surveillance and Pandemic Preparedness
_c['Pandey Phd, Rajesh']
264 1 _bAcademic Press
_c2023
300 _a p.
336 _btxt
_2rdacontent
337 _bc
_2rdamdedia
338 _bc
_2rdacarrier
650 0 _a
700 0 _aPandey Phd, Rajesh
856 4 0 _2Cyberlibris
_uhttps://international.scholarvox.com/netsen/book/88963922
_qtext/html
_a
520 _aGenomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference—moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness. - Highlights different aspects of genomic surveillance, from theory to implementation to inferences - Covers a broad range of infectious diseases, with emphasis on recent COVID-19 studies - Shares methods and approaches for sequencing-based pathogen detection, diagnostics, and surveillance - Facilitates international collaboration in drug and vaccine development
999 _c1326894
_d1326894