000			02622cam a2200277zu 4500
001			88964649
003			FRCYB88964649
005			20250429183111.0
006			m o d
007			cr un
008			250429s2021 fr | o|||||0|0|||eng d
020			_a9780128163641
035			_aFRCYB88964649
040			_aFR-PaCSA _ben _c _erda
100	1		_aKumar, Vijay
245	0	1	_aEmerging Concepts in Ribosome Structure, Biogenesis, and Function _c['Kumar, Vijay']
264		1	_bAcademic Press _c2021
300			_a p.
336			_btxt _2rdacontent
337			_bc _2rdamdedia
338			_bc _2rdacarrier
650		0	_a
700	0		_aKumar, Vijay
856	4	0	_2Cyberlibris _uhttps://international.scholarvox.com/netsen/book/88964649 _qtext/html _a
520			_aRibosome biogenesis is the process of making ribosomes which are responsible for mRNA translation into proteins. It is a tightly regulated process closely linked to nearly all biochemical and cellular processes, including cell division, growth, and development. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides a synthesized overview of all the parts engaged in this process. The book begins by providing an introduction to the ribosome factory, its origin, and its evolution of translation. It then goes on to describe ribosome structure including subunits, RNA, and protein components. Ribosome biogenesis and its emergence as a frontier research area for translational potential in cancer and other diseases are also discussed. In addition, the book explores current developments in ribosome research like the emergence of ribosomopathies, how deregulation of ribosome biogenesis can impact disease mechanisms and aging, and the discovery of specialized ribosomes that have specific functions that may translate differentially with consequences on normal and pathological processes. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides fundamental coverage and emerging research on ribosomes, biogenesis, and their structure and function and is a resourceful introduction for new researchers and those engaged in interdisciplinary ribosomal research. - Provides an overview of ribosome biogenesis and examines its involvement in cell transformation and cancerous growth - Covers disorders related to the ribosome (ribosomopathies) and explains the significance of ribosome dysfunction in human diseases - Includes commonly used methods to study ribosomes, such as polysome preparation, RNA profiling and proteomics, CryoEM, and Cell-free assays along with proper illustrations
999			_c1328585 _d1328585