000			02871cam a2200277zu 4500
001			88964862
003			FRCYB88964862
005			20250429183303.0
006			m o d
007			cr un
008			250429s2024 fr | o|||||0|0|||eng d
020			_a9780443161667
035			_aFRCYB88964862
040			_aFR-PaCSA _ben _c _erda
100	1		_aBanik, Bimal
245	0	1	_aGreen Approaches in Medicinal Chemistry for Sustainable Drug Design _bApplications _c['Banik, Bimal']
264		1	_bElsevier Science _c2024
300			_a p.
336			_btxt _2rdacontent
337			_bc _2rdamdedia
338			_bc _2rdacarrier
650		0	_a
700	0		_aBanik, Bimal
856	4	0	_2Cyberlibris _uhttps://international.scholarvox.com/netsen/book/88964862 _qtext/html _a
520			_aExtensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. - Highlights the need for adoption of sustainable and green chemistry pathways in drug development - Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these - Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability
999			_c1328998 _d1328998