000 02609cam a2200301zu 4500
001 88964913
003 FRCYB88964913
005 20250429183309.0
006 m o d
007 cr un
008 250429s2019 fr | o|||||0|0|||eng d
020 _a9780128178904
035 _aFRCYB88964913
040 _aFR-PaCSA
_ben
_c
_erda
100 1 _aEgbuna, Chukwuebuka
245 0 1 _aPhytochemicals as Lead Compounds for New Drug Discovery
_c['Egbuna, Chukwuebuka', 'Kumar, Shashank', 'Ifemeje, Jonathan C.']
264 1 _bElsevier Science
_c2019
300 _a p.
336 _btxt
_2rdacontent
337 _bc
_2rdamdedia
338 _bc
_2rdacarrier
650 0 _a
700 0 _aEgbuna, Chukwuebuka
700 0 _aKumar, Shashank
700 0 _aIfemeje, Jonathan C.
856 4 0 _2Cyberlibris
_uhttps://international.scholarvox.com/netsen/book/88964913
_qtext/html
_a
520 _aPhytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. - Presents fundamental concepts and factors affecting choice for plant-based products - Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward - Highlights recent advances in computational-based drug discovery - Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance
999 _c1329048
_d1329048