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041 _afre
042 _adc
100 1 0 _aPérillaud-Dubois, Claire
_eauthor
700 1 0 _a Bouthry, Elise
_eauthor
700 1 0 _a Kounis, Ilias
_eauthor
700 1 0 _a Roque-Afonso
_eauthor
700 1 0 _a Vauloup-Fellous, Christelle
_eauthor
245 0 0 _aWhen EBV serology needs a blot to reach a conclusion: A case report
260 _c2022.
500 _a81
520 _aA 14-year-old patient underwent a liver transplant. Three months after transplantation, EBV-associated lymphoma was suspected. EBV serologies before and after transplantation were particularly discrepant. Eighteen months before transplantation, the serological profile suggested a recent EBV primary infection; four months before transplantation, we had isolated anti-EBNA IgG; and five days after transplantation, the serological profile suggested a past infection. All EBV PCRs performed on whole blood were negative. Retrospectively, anti-EBV IgG immunoblots were performed. The blots showed no anti-EBV IgG before and until the day of liver transplantation. Five days after transplantation, slight bands of both IgG anti-p18 (VCA) and anti-EBNA-1 were found, without any other serological marker. These were probably due to passive transfers of IgG during surgery. There was therefore no argument for immunization against EBV before or after liver transplant for this patient.
786 0 _nAnnales de Biologie Clinique | 80 | 4 | 2022-07-01 | p. 385-388 | 0003-3898
856 4 1 _uhttps://shs.cairn.info/journal-annales-de-biologie-clinique-2022-4-page-385?lang=en
999 _c135669
_d135669