000 02213cam a2200193 4500500
005 20251012013129.0
041 _afre
042 _adc
100 1 0 _aWu, Hailong
_eauthor
700 1 0 _a Zhao, Fengming
_eauthor
700 1 0 _a Jia, Wenzhi
_eauthor
700 1 0 _a Li, Peng
_eauthor
245 0 0 _aThe brain-gut axis: the dawn of neurological disorders?
260 _c2025.
500 _a3
520 _aBackgroundOver the past two decades, the brain-gut axis has received increasing scholarly attention. However, few bibliometric analyses have systematically examined this area. We aimed to visualize the current status of research in this field, summarize hotspots, and present trends through a bibliometric analysis of published publications related to the brain-intestinal axis.MethodsPublications about the brain-gut axis were selected from the Web of Science Core Database (WoSCC) database. Countries/regions, institutions, authors, journals, references, and keywords in this field were visually analyzed using VOSviewer and CiteSpace software.ResultsA total of 3320 publications were eventually retrieved from 2000 to 2021. Publications on the brain-gut axis have increased year by year, especially in the last decade. The United States was the most prolific country (943, 28.404%), while Ireland was the country with the highest average number of article citations (156.03). Before 2011, most studies focused on the brain-gut axis, with irritable bowel syndrome being the most studied disorder; whereas in the last decade, most studies focused on the gut-brain axis, especially the microbial gut-brain axis, with neurodegenerative disorders being the most studied.ConclusionIn terms of global trends, research on the brain-gut axis is booming. Moreover, the role and therapeutic applications of the microbial-gut-brain axis in the progression of central nervous system (CNS) diseases, especially neurodegenerative diseases, are the focus of current research and future research trends.
786 0 _nAnnales de Biologie Clinique | 83 | 4 | 2025-09-03 | p. 372-394 | 0003-3898
856 4 1 _uhttps://shs.cairn.info/journal-annales-de-biologie-clinique-2025-4-page-372?lang=en&redirect-ssocas=7080
999 _c1528446
_d1528446