000			02040cam a2200193 4500500
005			20251012013151.0
041			_afre
042			_adc
100	1	0	_aSaouli, Sara _eauthor
700	1	0	_a Scellier, Guillaume _eauthor
700	1	0	_a Vernon, Virginie _eauthor
700	1	0	_a Melchior, Chloé _eauthor
245	0	0	_aDiagnostic tests for digestive malabsorption: Indications and interpretations
260			_c2025.
500			_a98
520			_aDigestive malabsorption is characterized by increased elimination of nutrients due to insufficient assimilation through the intestinal mucosa. Chronic diarrhea with greasy stools, combined with the presence of biological deficiencies, should raise the suspicion of malabsorption. The first-line test to confirm the diagnosis of malabsorption is a 24-hour fecalogram with a search for steatorrhea. If the diagnosis is confirmed, an etiological work-up should be carried out, combining oesogastroduodenal endoscopy with duodenal and bulbar biopsies (celiac disease, Biermer’s disease, lambliasis, Whipple’s disease), testing for antibodies specific to celiac disease and Biermer’s disease (anti-transglutaminase, anti-intrinsic factor, and anti-parietal cell antibodies), fecal elastase (exocrine pancreatic insufficiency), immunoglobulin weight assay, and plasma protein electrophoresis (primary immunodeficiency). Alpha-1-antitrypsin clearance should be performed in cases of associated edematous syndrome (exudative enteropathy). Once an organic etiology has been ruled out, respiratory tests may be performed, in particular a glucose breath test to check for small intestinal bacterial overgrowth (SIBO). In the absence of diagnostic tests available in France, cholestyramine may also be tried as a trial treatment in the event of bile acid malabsorption.
786	0		_nHépato-Gastro & Oncologie Digestive | 32 | 2 | 2025-03-05 | p. 161-167 | 2115-3310
856	4	1	_uhttps://shs.cairn.info/revue-hepato-gastro-oncologie-digestive-2025-2-page-161?lang=en&redirect-ssocas=7080
999			_c1528631 _d1528631