000			02124cam a2200265 4500500
005			20251214025814.0
041			_afre
042			_adc
100	1	0	_aBlanc, Frédéric _eauthor
700	1	0	_aBrangier, Antoine _eauthor
700	1	0	_aMouton, Aurélie _eauthor
700	1	0	_aMagnan, Nathaniel _eauthor
700	1	0	_aRabiant, Kevin _eauthor
700	1	0	_aAuxire, Pauline _eauthor
700	1	0	_aSchorr, Benoit _eauthor
700	1	0	_aRoche, Jean _eauthor
700	1	0	_aSoto, Maria _eauthor
700	1	0	_aDelrieu, Julien _eauthor
245	0	0	_aTreatment of psychological and behavioral symptoms in dementia with Lewy bodies and Parkinson’s disease dementia: Literature review and Delphi consensus
260			_c2025.
500			_a90
520			_aIntroduction Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are frequently associated with psychological and behavioral symptoms (PBSs). Treatment for these symptoms is validated by varying levels of evidence Method We conducted a review of the literature on the treatment of PBSs in DLB and PDD from 2009 to 2023 and formulated treatment recommendations. When evidence from the literature was insufficient, the Delphi method was used to reach a consensus. Results The following recommendations were proposed: for intrusive hallucinations with insight preserved, donepezil or rivastigmine; for delusion and Capgras syndrome (Delphi), low doses of clozapine; for depression, sertraline, venlafaxine, or mirtazapine (Delphi); for REM sleep behavior disorder (RBD), immediate-release melatonin; for frontal syndrome, sertraline or paroxetine first, followed by trazodone (Delphi); for catatonia, lorazepam. Conclusion These recommendations should help improve the management of PBSs in DLB and PDD, thereby enhancing the quality of life of patients and caregivers.
786	0		_nGériatrie et Psychologie Neuropsychiatrie du Vieillissement | 23 | 2 | 2025-09-20 | p. 235-253 | 2115-8789
856	4	1	_uhttps://stm.cairn.info/journal-geriatrie-et-psychologie-neuropsychiatrie-du-vieillissement-2025-2-page-235?lang=en&redirect-ssocas=7080
999			_c1573057 _d1573057