000 02727cam a2200397 4500500
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041 _afre
042 _adc
100 1 0 _aUldahl, Ada
_eauthor
700 1 0 _a Sterner, Therese
_eauthor
700 1 0 _a Bruze, Magnus
_eauthor
700 1 0 _a Dahlin, Jakob
_eauthor
700 1 0 _a Von Kobyletzki, Laura
_eauthor
700 1 0 _a Svensson, Åke
_eauthor
700 1 0 _a Kiotseridis, Hampus
_eauthor
700 1 0 _a Tunsäter, Alf
_eauthor
700 1 0 _a Svedman, Cecilia
_eauthor
245 0 0 _aAtopy patch testing and associations with atopic conditions and specific IgE tests: a population-based study in adolescents
260 _c2023.
500 _a12
520 _aBackground. The clinical usefulness of the atopy patch test (APT) is unclear for investigating aeroallergen- and food-triggered atopic dermatitis (AD). Objectives. This study aimed to assess the prevalence of positive APT reactions in a population of adolescents and investigate possible associations between the APT, specific serum (s) immunoglobulin E (IgE) tests, self-reported atopic conditions and health-related quality of life. Materials & Methods. A population-based study was performed on 211 adolescents (13-14 years old). Collected data included questionnaires, an APT with food and aeroallergens and s-IgE tests. Results. Positive APT reactions were observed in 9.0% (19/211) of the adolescents. Timothy grass was the top allergen with 11 (5.2%) positive reactions, followed by cat dander (2.8%) and house dust mites (2.4%). Rhinoconjunctivitis increased the odds of any positive APT (crude odds ratio: 3.32; 95% confidence interval [CI]: 1.17–9.40), particularly when an APT was positive for aeroallergens (odds ratio: 5.02, 95% CI: 1.54-16.42). There was no association between a positive APT and AD. Four adolescents without AD and no IgE-sensitization had a positive APT. Conclusion. Based on a population of adolescents, the APT is associated with rhinoconjunctivitis but not AD. This finding should be taken into consideration in further attempts to clarify the role of the APT in the clinical setting.
690 _aatopy patch test
690 _adelayed hypersensitivity
690 _aepidemiology
690 _aatopic dermatitis
690 _arhinoconjunctivitis
690 _aadolescents
690 _aatopy patch test
690 _adelayed hypersensitivity
690 _aepidemiology
690 _aatopic dermatitis
690 _arhinoconjunctivitis
690 _aadolescents
786 0 _nEuropean Journal of Dermatology | 21 | 3 | 2023-09-26 | p. 384-393 | 1167-1122
856 4 1 _uhttps://shs.cairn.info/journal-european-journal-of-dermatology-2022-3-page-384?lang=en
999 _c160362
_d160362