| 000 | 02348cam a2200301 4500500 | ||
|---|---|---|---|
| 005 | 20250112032609.0 | ||
| 041 | _afre | ||
| 042 | _adc | ||
| 100 | 1 | 0 |
_aFukuzono, Maki _eauthor |
| 700 | 1 | 0 |
_a Okiyama, Naoko _eauthor |
| 700 | 1 | 0 |
_a Iwasaki, Riko _eauthor |
| 700 | 1 | 0 |
_a Endo, Ruriko _eauthor |
| 700 | 1 | 0 |
_a Sasaki, Katsuhito _eauthor |
| 700 | 1 | 0 |
_a Inoue, Sae _eauthor |
| 700 | 1 | 0 |
_a Nomura, Toshifumi _eauthor |
| 245 | 0 | 0 | _aIntravenous immunoglobulin-induced thrombocytopenia: a case report and review of the literature |
| 260 | _c2023. | ||
| 500 | _a10 | ||
| 520 | _aBackground. Intravenous immunoglobulin (IVIG), a pooled blood product acquired from multiple healthy donors, is an effective treatment for various types of autoimmune diseases, haematological disorders, and infectious diseases. Adverse haematological events such as throm-bocytopenia are rarely caused by IVIG. Objectives. To investigate the phenomenon of IVIG-induced thrombocytopenia. Materials & Methods. A case study and a review of the previous literature based on a search using MEDLINE (PubMed) and ICHUSHI (for Japanese literature) electronic databases. Results. The present case of dermatomyositis exhibited two episodes of IVIG-induced thrombocytopenia, which occurred a few days after initiating IVIG and was significant within two weeks without haemorrhagic symptoms. Spontaneous remission of thrombocytopenia was repeatedly observed. Based on a review of five cases, the underlying disorders were autoimmune bullous diseases in three of the five cases. Polyethylene glycol-treated human immunoglobulin products were used in three of the five cases. The clinical course of IVIG-induced thrombocytopenia was similar to that in our present case. Conclusion. Because of the rarity of severe haemorrhagic symptoms and spontaneous remission of IVIG-induced thrombocytopenia, discontinuation of IVIG due to thrombocytopenia is not straightforward. | ||
| 690 | _athrombocytopenia | ||
| 690 | _aadverse event | ||
| 690 | _aintravenous immunoglobulin | ||
| 690 | _athrombocytopenia | ||
| 690 | _aadverse event | ||
| 690 | _aintravenous immunoglobulin | ||
| 786 | 0 | _nEuropean Journal of Dermatology | 21 | 3 | 2023-09-26 | p. 373-376 | 1167-1122 | |
| 856 | 4 | 1 | _uhttps://shs.cairn.info/journal-european-journal-of-dermatology-2022-3-page-373?lang=en |
| 999 |
_c160372 _d160372 |
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