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041 _afre
042 _adc
100 1 0 _aDi Martino, Vincent
_eauthor
700 1 0 _aWeil-Verhoeven, Delphine
_eauthor
700 1 0 _aBouiller, Kévin
_eauthor
245 0 0 _aBacterial infections during cirrhosis: Epidemiology, pathophysiology, and contributing factors
260 _c2025.
500 _a49
520 _aPatients with cirrhosis are more susceptible to bacterial infections, especially those involving multidrug-resistant germs. They are the leading cause of organ failure and mortality and a major cause of hospitalization. The bacteria most commonly involved are from the digestive tract, such as Escherichia coli, Klebsiella pneumoniae, and enterococci. The pathophysiology is based on an increase in intestinal permeability, which is the consequence of qualitative and quantitative changes in gut microbiota associated with an alteration in digestive tract mucosa, mainly intestinal. Systemic infection, secondary to bacterial translocation, is made possible by the constant failure of immune responses during cirrhosis, leading to uncontrolled proliferation and dissemination of bacteria.
786 0 _nHépato-Gastro & Oncologie Digestive | 32 | 4 | 2025-04-25 | p. 334-342 | 2115-3310
856 4 1 _uhttps://stm.cairn.info/journal-hepato-gastro-oncologie-digestive-2025-4-page-334?lang=en&redirect-ssocas=7080
999 _c1671580
_d1671580