000 01087cam a2200169 4500500
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041 _afre
042 _adc
100 1 0 _aRoblin, Xavier
_eauthor
700 1 0 _aBarrau, Mathilde
_eauthor
245 0 0 _aToward personalized medicine with anti-TNF? Not yet . . .
260 _c2024.
500 _a36
520 _aThere is a link between the presence of the HLA DQA1-05 allele and the development of anti-TNF antibodies. Testing for the HLA DQA1-05 variant makes it possible to isolate patients with a high immunogenic risk under anti-TNF therapy, but its sensitivity and specificity are insufficient to propose precise algorithms based on the results. This test, therefore, remains a decision-support tool. Elevated IFX clearance identifies the patients at greatest risk of requiring a colectomy to treat severe acute colitis.
786 0 _nHépato-Gastro & Oncologie Digestive | 31 | 1 | 2024-01-01 | p. 29-32 | 2115-3310
856 4 1 _uhttps://stm.cairn.info/journal-hepato-gastro-oncologie-digestive-2024-1-page-29?lang=en&redirect-ssocas=7080
999 _c1718854
_d1718854