000			01942cam a2200265 4500500
005			20260322004802.0
041			_afre
042			_adc
100	1	0	_aProthe, Carole _eauthor
700	1	0	_aFathallah, Nadia _eauthor
700	1	0	_aBarré, Amélie _eauthor
700	1	0	_aPommaret, Élise _eauthor
700	1	0	_aRentien, Anne-Laure _eauthor
700	1	0	_aRoland, Déborah _eauthor
700	1	0	_aAlam, Amine _eauthor
700	1	0	_aSkoufou, Maria _eauthor
700	1	0	_aBenfredj, Paul _eauthor
700	1	0	_ade Parades, Vincent _eauthor
245	0	0	_aNon-fistulizing perianal lesions in Crohn’s disease: A practical review and therapeutic implications
260			_c2026.
500			_a23
520			_aDespite their frequency, non-fistulizing perianal lesions in Crohn’s disease remain underexplored. In contrast to fistulas and abscesses, their management is based on poorly standardized data. Their polymorphic clinical presentation can delay diagnosis. Clinical examination is essential and should be complemented by pelvic MRI to exclude underlying complications such as fistulas or abscesses. Treatment primarily relies on anti-TNFα agents, often in combination with immunosuppressants. Other biologic therapies, including JAK inhibitors, offer promising prospects, despite a low level of evidence with limited clinical data on non-fistulizing lesions available. Surgery is reserved for fibrotic lesions or degenerative complications. Long-term follow-up is mandatory due to the risk of anal cancer in chronic cases. This mini review provides a practical overview of the diagnostic, evaluative, and therapeutic strategies for these underrecognized manifestations of perianal Crohn’s disease.
786	0		_nHépato-Gastro & Oncologie Digestive | 33 | 1 | 2026-02-10 | p. 20-30 | 2115-3310
856	4	1	_uhttps://stm.cairn.info/journal-hepato-gastro-oncologie-digestive-2026-1-page-20?lang=en&redirect-ssocas=7080
999			_c1743083 _d1743083