000			01603cam a2200169 4500500
005			20250112044403.0
041			_afre
042			_adc
100	1	0	_aBry-Gauillard, Hélène _eauthor
700	1	0	_a Pasquier, Maud _eauthor
245	0	0	_aManagement of infertility in women with hypogonadotropic hypogonadism
260			_c2023.
500			_a31
520			_aHypogonadotropic hypogonadism is caused by a deficit or a dysfunction of the gonadotropic axis, resulting in anovulation. The deficit may be total, with collapsed gonadotropins, or partial, with a less marked hormonal picture. Hypogonadism may be congenital, as in Kallmann syndrome, or acquired secondary to hypothalamic-pituitary pathologies, for example. Management of infertility depends on the etiology of hypogonadism, but also on any associated subfertility factors, which should be systematically investigated before ovulation is induced. This review discusses treatments specific to certain etiologies, such as hyperprolactinemia and hypothalamic amenorrhea, and the particularities of ovulation induction in hypogonadotropic hypogonadism. Ovulation induction with gonadotropins can, in some cases, be difficult to manage, due to the difficulty of achieving monofollicular recruitment. The prognosis for pregnancy is generally excellent, even in cases of complete hypogonadism or hypogonadism associated with other pituitary deficiencies.
786	0		_nMédecine de la Reproduction | 25 | 3 | 2023-07-01 | p. 270-278 | 2650-8427
856	4	1	_uhttps://shs.cairn.info/journal-medecine-de-la-reproduction-2023-3-page-270?lang=en
999			_c190504 _d190504