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041 _afre
042 _adc
100 1 0 _aChevaux, Jean-Baptiste
_eauthor
700 1 0 _aRay, Céline
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700 1 0 _aJézéquel, Julien
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700 1 0 _aMochet, Mikael
_eauthor
700 1 0 _aKoch, Stéphane
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700 1 0 _aHoudard, Anne
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700 1 0 _aGronier, Olivier
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700 1 0 _aDurand, Fanny
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700 1 0 _aBoinette, Aurélien
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700 1 0 _aBarrué, Cécile
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700 1 0 _aVanbiervliet, Geoffroy
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700 1 0 _aSylvant, Olivier
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700 1 0 _aGincul, Rodica
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700 1 0 _aImbert, Dominique
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245 0 0 _aRecommendations from the French Society for Digestive Endoscopy (SFED) and the Nursing Association for Training in Endoscopy (GIFE) for paramedical staff working in digestive endoscopy technical support services
260 _c2024.
500 _a68
520 _aThe diagnosis of cholangitis should be made in the presence of chronic cholestasis, after ruling out chronic viral hepatitis and medication use, and provided hepatic ultrasound is normal. The clinical signs of cholangitis are not specific and include asthenia and pruritus. Anti-mitochondrial antibody (AMA) testing is the first key step in diagnosis. When positive, a diagnosis of primary biliary cholangitis (PBC) is made. PBC is a destructive autoimmune disease of the small bile ducts, mainly affecting women aged around 50. First-line treatment with ursodesoxycholic acid (UDCA) slows the progression to cirrhosis and its complications. When anti-mitochondrial antibodies are negative, cholangio-MRI is recommended to identify bile duct strictures, which may suggest a diagnosis of primary sclerosing cholangitis (PSC). This inflammatory disease of the large bile ducts tends to affect men aged around 40 and is very frequently associated with an IBD. Treatment of PSC is also based on UDCA. Complications of PSC include angiocholitis, cholangiocarcinoma, and cirrhosis with a risk of decompensation. When associated with IBD, there is also an increased risk of colon cancer, justifying annual ultrasound screening of the bile ducts as well as annual colon screening by colonoscopy.
786 0 _nHépato-Gastro & Oncologie Digestive | 31 | 7 | 2024-09-25 | p. 655-661 | 2115-3310
856 4 1 _uhttps://stm.cairn.info/journal-hepato-gastro-oncologie-digestive-2024-7-page-655?lang=en&redirect-ssocas=7080
999 _c1921221
_d1921221