| 000 | 01221cam a2200217 4500500 | ||
|---|---|---|---|
| 005 | 20250112065509.0 | ||
| 041 | _afre | ||
| 042 | _adc | ||
| 100 | 1 | 0 |
_aWang, Wen-Ming _eauthor |
| 700 | 1 | 0 |
_a Jin, Hong-Zhong _eauthor |
| 245 | 0 | 0 | _aHeat shock proteins and psoriasis |
| 260 | _c2019. | ||
| 500 | _a72 | ||
| 520 | _aPsoriasis is a chronic disfiguring skin condition which may be induced or exacerbated by stress. Heat shock proteins (HSPs), as molecular chaperones, play a central role in protein folding and cellular protein homeostasis. The many different functions of HSPs in the cell depend on the specific HSP involved. HSPs play crucial roles in inflammation and immune reactions, and have emerged as promising therapeutic targets. In this review, we compile current lines of evidence concerning the roles and molecular mechanisms of HSPs that lead to the occurrence and development of psoriasis. | ||
| 690 | _aprotein folding | ||
| 690 | _aheat shock proteins | ||
| 690 | _apsoriasis | ||
| 690 | _amicrobe | ||
| 786 | 0 | _nEuropean Journal of Dermatology | 29 | 2 | 2019-03-01 | p. 121-125 | 1167-1122 | |
| 856 | 4 | 1 | _uhttps://shs.cairn.info/revue-european-journal-of-dermatology-2019-2-page-121?lang=en |
| 999 |
_c242196 _d242196 |
||