000 01946cam a2200289 4500500
005 20250112070719.0
041 _afre
042 _adc
100 1 0 _aTomson, Torbjörn
_eauthor
700 1 0 _a Battino, Dina
_eauthor
700 1 0 _a Bromley, Rebecca
_eauthor
700 1 0 _a Kochen, Silvia
_eauthor
700 1 0 _a Meador, Kimford J.
_eauthor
700 1 0 _a Pennell, Page
_eauthor
700 1 0 _a Thomas, Sanjeev V.
_eauthor
245 0 0 _aManagement of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy
260 _c2019.
500 _a67
520 _aThe risks associated with use of antiepileptic drugs during pregnancy are a major concern for all women with epilepsy with childbearing potential. These risks have to be balanced against foetal and maternal risks associated with uncontrolled seizures. This report from the International League Against Epilepsy Task Force on Women and Pregnancy aims to provide a summary of relevant data on these risks as a basis for expert opinion recommendations for the management of epilepsy in pregnancy. The report reviews data on maternal and foetal risks associated with seizures as well as teratogenic risks associated with antiepileptic drug exposure, including effects on intrauterine growth, major congenital malformations, and developmental and behavioural outcomes. The impact of pregnancy on seizure control and on the pharmacokinetics of antiepileptic drugs are also discussed. This information is used to discuss how treatment may be optimized before conception and further managed during pregnancy.
690 _apregnancy
690 _ateratogenesis
690 _aantiepileptic drugs
690 _afoetal risks
690 _aepilepsy
786 0 _nEpileptic Disorders | Vol 21 | 6 | 2019-06-01 | p. 497-517 | 1294-9361
856 4 1 _uhttps://shs.cairn.info/revue-epileptic-disorders-2019-6-page-497?lang=en
999 _c247079
_d247079