| 000 | 03480cam a2200373 4500500 | ||
|---|---|---|---|
| 005 | 20250112073725.0 | ||
| 041 | _afre | ||
| 042 | _adc | ||
| 100 | 1 | 0 |
_aJurek, Lucie _eauthor |
| 700 | 1 | 0 |
_a Herrmann, Mathieu _eauthor |
| 700 | 1 | 0 |
_a Bonze, Mathilde _eauthor |
| 700 | 1 | 0 |
_a Brunet, Sophie _eauthor |
| 700 | 1 | 0 |
_a Padovan, Catherine _eauthor |
| 700 | 1 | 0 |
_a Dorey, Jean-Michel _eauthor |
| 245 | 0 | 0 | _aSymptômes neuropsychiatriques dans la maladie à corps de Lewy : revue de la littérature |
| 260 | _c2018. | ||
| 500 | _a11 | ||
| 520 | _aLa maladie à corps de Lewy (MCL) est une pathologie neurodégénérative fréquente, seconde en termes de prévalence après la maladie d’Alzheimer. Son diagnostic clinique repose sur des fluctuations cognitives et motrices, des hallucinations visuelles précoces et un syndrome parkinsonien ; récemment les nouveaux critères de MCL ont ajouté les troubles du comportement en sommeil paradoxal (TCSP). Les symptômes neuropsychiatriques (SNP) de la MCL sont plus nombreux, plus sévères et plus précoces que dans les autres pathologies neurodégénératives. Ils sont parfois au premier plan devant les symptômes moteurs et cognitifs. Leur reconnaissance constitue un enjeu diagnostique et thérapeutique important. L’objectif de cet article est de proposer une synthèse sur la phénoménologie, l’étiopathogénie, et le traitement des SNP dans la MCL. | ||
| 520 | _aDementia with Lewy bodies (DLB) is a common neurodegenerative disease, second in terms of prevalence after Alzheimer’s disease (AD). DLB may be suspected according to three core features which are cognitive and motor fluctuations, early visual hallucinations and parkinsonism; and more recently, according to the new criteria, REM sleep behavior disorder (RBD). Behavorial and psychological symptoms associated with DLB are more frequent, more severe and appear earlier than those found in other neurodegenerative diseases. They may be at the forefront and are a major diagnostic and therapeutic challenge. An improved knowledge of the pathophysiology and phenomenology associated to these symptoms can facilitate their identification as well as eliminating differential diagnoses. Managing these symptoms may require drugs when hallucinations are overwhelming and induce behavorial disorders. However, psychotropic medications are not well tolerated in this specific population and some antipsychotic drugs cannot be prescribed due to their side effects. Although further studies are needed on this subject, non-interventional treatments such as therapeutic strategies based on the patients and their caregivers appear to be essential. This paper offers a review which aims to help clinicians to identify behavioral and psychological symptoms in DLB and treat them in their daily practice. | ||
| 690 | _adépression | ||
| 690 | _amaladie à corps de Lewy | ||
| 690 | _ahallucinations | ||
| 690 | _aanxiété | ||
| 690 | _adémence à corps de Lewy | ||
| 690 | _asymptômes comportementaux | ||
| 690 | _aanxiety | ||
| 690 | _ahallucinations | ||
| 690 | _adepression | ||
| 690 | _abehavioral symptoms | ||
| 690 | _adementia with Lewy bodies | ||
| 690 | _aLewy body disease | ||
| 786 | 0 | _nGériatrie et Psychologie Neuropsychiatrie du Vieillissement | 16 | 1 | 2018-03-01 | p. 87-95 | 2115-8789 | |
| 856 | 4 | 1 | _uhttps://shs.cairn.info/revue-geriatrie-et-psychologie-neuropsychiatrie-du-vieillissement-2018-1-page-87?lang=fr |
| 999 |
_c259393 _d259393 |
||