000 01790cam a2200241 4500500
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041 _afre
042 _adc
100 1 0 _aGhozzi, Mariam
_eauthor
700 1 0 _a Mechi, Fatma
_eauthor
700 1 0 _a Salem, Alma Ben
_eauthor
700 1 0 _a El Ahmer, Ikram
_eauthor
700 1 0 _a Mbarki, Donia Rachel
_eauthor
700 1 0 _a Melayah, Sarra
_eauthor
700 1 0 _a Mankai, Amani
_eauthor
700 1 0 _a Ghedira, Ibtissem
_eauthor
245 0 0 _aSerological screening for celiac disease, using endomysial antibodies, in patients with rheumatoid arthritis
260 _c2023.
500 _a64
520 _aBackground and aims Celiac disease (CD) and rheumatoid arthritis (RA) are both multi-factorial chronic inflammatory auto-immune diseases. In this retrospective study, we determined the frequency of CD in patients with RA using IgA anti-endomysial antibodies (EmA) and attempted to explain this association. Patients and methods Indirect immunofluorescence on human umbilical cord was used to detect EmA in 215 patients with seropositive RA collected over a four-year-period. Two thousand five hundred healthy blood donors (HBDs) served as the control group. Results Among the 215 patients with RA, 12 (9 females) were found positive for EmA while only 7 were positive for EmA in the control group. The frequency of EmA was significantly higher in RA patients than in HBDs (5.58% vs. 0.28%, p Conclusion Patients with RA can be considered as a high-risk group for CD based on the high frequency of EmA positivity observed in our study.
786 0 _nAnnales de Biologie Clinique | 81 | 6 | 2023-11-01 | p. 569-575 | 0003-3898
856 4 1 _uhttps://shs.cairn.info/journal-annales-de-biologie-clinique-2023-6-page-569?lang=en&redirect-ssocas=7080
999 _c404568
_d404568