000 01780cam a2200193 4500500
005 20250121081742.0
041 _afre
042 _adc
100 1 0 _aChaussade, Stanislas
_eauthor
700 1 0 _a Corre, Felix
_eauthor
700 1 0 _a Coriat, Romain
_eauthor
700 1 0 _a Terris, Benoit
_eauthor
245 0 0 _aEvaluation of the risk of lymph node metastases in superficial T1 rectal cancer: The current role of endoscopic treatment and future perspectives
260 _c2024.
500 _a31
520 _aT1 colorectal cancers that infiltrate the submucosa have a risk of lymph node metastasis of about 10%, which is higher than in the colon. The criteria for additional treatment after endoscopic resection have been modified in the latest version of the French recommendations, opening up the possibility of curative resection in the case of lesions deeply invading the submucosa (sm2, sm3), provided there are no histopronostic factors associated with a poor prognosis. These factors include lymphovascular and neural invasion, budding ≥ 2, and poor tumor differentiation. Anatomopathological examination of the endoscopic specimen is therefore essential and a second opinion by an experienced pathologist may be recommended. In these cases, a monobloc resection is required, which has been made possible by advances in submucosal dissection techniques. The use of artificial intelligence, immunoscore, and nomograms may help to predict the risk of lymph node metastasis and tailor treatment approaches according to age and comorbidities.
786 0 _nHépato-Gastro & Oncologie Digestive | 31 | 2 | 2024-02-01 | p. 211-220 | 2115-3310
856 4 1 _uhttps://shs.cairn.info/journal-hepato-gastro-oncologie-digestive-2024-2-page-211?lang=en&redirect-ssocas=7080
999 _c498848
_d498848