000			02195cam a2200289 4500500
005			20250121133410.0
041			_afre
042			_adc
100	1	0	_aSanz, Leandro R.D. _eauthor
700	1	0	_a Laureys, Steven _eauthor
700	1	0	_a Gosseries, Olivia _eauthor
245	0	0	_aDisorders of consciousness: Behavioral and neuroimaging studies
260			_c2018.
500			_a17
520			_aDisorders of consciousness after a coma are both a clinical challenge for caregivers and a unique research opportunity on human consciousness for neuroscientists. To set standards in this constantly evolving field, a nosological classification now clearly defines the different states of impaired consciousness and their diagnostic clinical signs. The gold standard behavioral evaluation of these patients is based on standardized scales that must be administered repeatedly. However, the sole clinical examination is not self-sufficient as sensorimotor impairments, aphasia, or fluctuations of vigilance levels can conceal the presence of conscious awareness. New methods using neuroimaging and neurophysiology, combined with innovative computational tools, can complement the clinical diagnosis and help assess these patients more accurately. Regarding treatment, non-invasive neurostimulation and pharmacological agents have demonstrated positive effects on recovery, but larger scale placebo-controlled clinical trials are needed to determine their efficacy and response rate more accurately. A multimodal integration of these new diagnostic and therapeutic techniques is necessary to offer patients with severe brain injury a more personalized and adapted form of care.
690			_aprognosis
690			_acoma
690			_aneurophysiology
690			_aconsciousness disorders
690			_adiagnosis
690			_atreatment
690			_avegetative state/unresponsive wakefulness syndrome
690			_aminimally conscious state
690			_aneuroimaging
786	0		_nRevue de neuropsychologie | Volume 10 | 4 | 2018-12-13 | p. 313-321 | 2101-6739
856	4	1	_uhttps://shs.cairn.info/journal-revue-de-neuropsychologie-2018-4-page-313?lang=en&redirect-ssocas=7080
999			_c574474 _d574474