000 02504cam a2200241 4500500
005 20250121154737.0
041 _afre
042 _adc
100 1 0 _aVeraldi, Stefano
_eauthor
700 1 0 _a Faraci, Andrea G.
_eauthor
700 1 0 _a Valentini, Davide
_eauthor
700 1 0 _a Bottini, Silvia
_eauthor
245 0 0 _aTropical ulcers: the first imported cases and review of the literature
260 _c2021.
500 _a49
520 _aBackground: A tropical ulcer is a bacterial necrotizing disease of the skin, with an acute or chronic clinical course, caused by anaerobic bacteria, notably Fusobacteria spp. Objectives: We present six Italian tourists who acquired tropical ulcers in tropical and subtropical countries. Materials & Methods: Four males and two females acquired a skin ulcer during trips to Brazil, Malaysia, Fiji Islands, Zambia, Tanzania and India. In all patients, medical history, physical and dermatological examination, laboratory tests, bacteriological examinations and biopsy were carried out. Results: All patients were in good general health. All patients stated that the ulcer was caused by a trauma. No fever was reported. Neither lymphangitis nor lymphadenopathy were detected. The ulcer was located on a forearm in one patient, on a leg in two and on an ankle in three patients. All ulcers were malodorous and painful. Laboratory tests revealed mild leucocytosis and a mild increase in erythrocyte sedimentation rate and C-reactive protein. Results of bacteriological examinations revealed the presence of Fusobacterium spp. in five patients. Other bacteria were identified in all patients. Histopathological examination showed: necrosis of the epidermis and dermis; vascular dilatation; oedema in the dermis; massive infiltration with neutrophils, lymphocytes and histiocytes; and fragmented collagen bundles. No signs of vasculitis were observed. All patients were successfully treated with oral metronidazole (1 g/day for two weeks) and, according to antibiograms, with different systemic antibiotics. Conclusion: To our knowledge, these are the first cases of tropical ulcers reported in Western tourists
690 _aFusobacterium ulcerans
690 _aFusobacteria spp.
690 _atropical ulcer
690 _aanaerobic bacteria
786 0 _nEuropean Journal of Dermatology | 31 | 1 | 2021-01-01 | p. 75-80 | 1167-1122
856 4 1 _uhttps://shs.cairn.info/revue-european-journal-of-dermatology-2021-1-page-75?lang=en&redirect-ssocas=7080
999 _c603197
_d603197