| 000 | 02878cam a2200337 4500500 | ||
|---|---|---|---|
| 005 | 20250121154901.0 | ||
| 041 | _afre | ||
| 042 | _adc | ||
| 100 | 1 | 0 |
_aChen, Zerong _eauthor |
| 700 | 1 | 0 |
_a Wang, Yiyi _eauthor |
| 700 | 1 | 0 |
_a Lan, Xiaomeng _eauthor |
| 700 | 1 | 0 |
_a Yang, Min _eauthor |
| 700 | 1 | 0 |
_a Ding, Li _eauthor |
| 700 | 1 | 0 |
_a Li, Gaojie _eauthor |
| 700 | 1 | 0 |
_a Hong, Peizhen _eauthor |
| 700 | 1 | 0 |
_a Bai, Yinling _eauthor |
| 700 | 1 | 0 |
_a Liu, Yi _eauthor |
| 700 | 1 | 0 |
_a Li, Wei _eauthor |
| 245 | 0 | 0 | _aNomogram for accurate and quantitative prediction of the risk of psoriatic arthritis in Chinese adult patients with moderate and severe plaque psoriasis |
| 260 | _c2021. | ||
| 500 | _a83 | ||
| 520 | _aBackground: Psoriatic arthritis (PsA) is an inflammatory form of arthritis that appears approximately 7-10 years after psoriasis and remains undiagnosed in most of patients. Currently, only a few quantitative and succinct PsA-risk prediction models are available. Objectives: The aim of this study was to establish and validate a prediction model for quantitatively assessing the risk of PsA in moderate and severe plaque psoriasis patients. Materials & Methods: A non-interventional and cross-sectional study was conducted. Demographic, clinical, and laboratory records were collected and blindly reviewed. Logistic regression was used to develop this prediction model. With C-index and calibration curve, internal validation was performed. Five-fold cross validation, external validation and decision curve analysis (DCA) were also applied to assess this model. Results: Among 405 patients, 111 patients had PsA. Arthralgia (OR = 39.346; 95% CI: 20.139-82.579), C-reactive protein (OR = 2.008; 95% CI: 1.051-3.838), lymphocyte level (OR = 0.341; 95% CI: 0.177-0.621), hypertension (OR = 0.235; 95% CI: 0.077-0.660) and disease duration (OR = 1.033; 95% CI: 0.998-1.071) were identified as potential predictors affecting the risk of transition from moderate and severe PsO to PsA. C-index for the prediction nomogram was 0.911 (95% CI: 0.879-0.943), and was confirmed to be 0.905 through 1000-time bootstrapping internal validation. Cross validation and external validation were preformed and proved the accuracy and generalizability of this prediction model. Conclusion: This study establishes a quantitative predictive nomogram with good predictive power for assessing the risk of PsA in patients with moderate and severe PsO. | ||
| 690 | _apsoriasis | ||
| 690 | _aprediction model | ||
| 690 | _aplaque psoriasis (PsO) | ||
| 690 | _anomogram | ||
| 690 | _arisk | ||
| 690 | _apsoriatic arthritis (PsA) | ||
| 786 | 0 | _nEuropean Journal of Dermatology | 31 | 4 | 2021-07-01 | p. 499-507 | 1167-1122 | |
| 856 | 4 | 1 | _uhttps://shs.cairn.info/revue-european-journal-of-dermatology-2021-4-page-499?lang=en&redirect-ssocas=7080 |
| 999 |
_c603614 _d603614 |
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