000			02140cam a2200253 4500500
005			20250121162735.0
041			_afre
042			_adc
100	1	0	_aFalsaperla, Raffaele _eauthor
700	1	0	_a Mauceri, Laura _eauthor
700	1	0	_a Motta, Milena _eauthor
700	1	0	_a Prezioso, Giovanni _eauthor
700	1	0	_a Ruggieri, Martino _eauthor
700	1	0	_a Pisani, Francesco _eauthor
245	0	0	_aBeyond neonatal seizures - epileptic evolution in preterm newborns: a systematic review and meta-analysis
260			_c2022.
500			_a20
520			_aObjective. To assess the potential risk of developing epilepsy in preterm newborns with neonatal seizures (NS). Two electronic databases (PubMed and Web of Sciences) were searched from inception to December 2020. Studies that investigated the outcome of epilepsy in neonates with NS were included.Methods. Case-control, cross-sectional and cohort studies were included. Data synthesis was undertaken via systematic review and meta-analysis of available evidence. All review stages were conducted by three independent reviewers. We analysed data on neonates with NS who developed post-neonatal epilepsy (PNE) based on the data reported in the selected articles. We then investigated the development of PNE in term and preterm neonates.Results. The initial search led to 568 citations, of which 12 were selected for the review and six were eligible for meta-analysis. Results of the meta-analysis showed no significant difference in the risk of developing PNE between full-term infants with NS (pooled OR [pOR]=0.92: 95% CI: 0.58-1.44) and preterm neonates.Significance. Gestational age does not seem to be an independent predictor for the development of PNE in neonates with NS. More data are needed to explore the relationship between seizures in the neonatal period and epilepsy later in life.
690			_apreterm infants
690			_aseizure
690			_anewborns
786	0		_nEpileptic Disorders | Vol 24 | 1 | 2022-01-01 | p. 140-150 | 1294-9361
856	4	1	_uhttps://shs.cairn.info/revue-epileptic-disorders-2022-1-page-140?lang=en&redirect-ssocas=7080
999			_c612127 _d612127