000 02411cam a2200301zu 4500
001 88817671
003 FRCYB88817671
005 20250107212123.0
006 m o d
007 cr un
008 250107s2013 fr | o|||||0|0|||eng d
020 _a9780123971654
035 _aFRCYB88817671
040 _aFR-PaCSA
_ben
_c
_erda
100 1 _aShapiro, Jay R.
245 0 1 _aOsteogenesis Imperfecta
_bA Translational Approach to Brittle Bone Disease
_c['Shapiro, Jay R.', 'Byers, Peter H.', 'Glorieux, Francis H.']
264 1 _bElsevier Science
_c2013
300 _a p.
336 _btxt
_2rdacontent
337 _bc
_2rdamdedia
338 _bc
_2rdacarrier
650 0 _a
700 0 _aShapiro, Jay R.
700 0 _aByers, Peter H.
700 0 _aGlorieux, Francis H.
856 4 0 _2Cyberlibris
_uhttps://international.scholarvox.com/netsen/book/88817671
_qtext/html
_a
520 _aOsteogenesis Imperfecta is the first translational reference professionals can turn to for a source of comprehensive information on this disorder. Although several reviews of the field have been published in various journals, there is no other single source for a compendium of current information. Separate chapters discuss each of the several clinical features of OI. Ethical issues related to OI are discussed, as is the importance of nutrition in managing the OI child and the OI adult. The role of physical medicine and rehabilitation for OI patients is also presented, along with the current status of OI medical treatment and the prospects for genetic engineering in the future. The text also provides the orthopedic surgeon with an advanced discussion of surgical techniques applicable to OI. Incorporates chapters and information on the ethical issues related to osteogenesis imperfecta (OI) as will the importance of nutrition in managing the OI child and the OI adult Offers new insights into the underlying mechanisms of collagen biochemistry as related to OI as well as a presentation of intracellular collagen processing and the expanded role of protein chaperones in OI Discusses the role of physical medicine and rehabilitation for OI patients and the current status of OI medical treatment as well as prospects for genetic engineering in the future Provides a unique overview for the orthopedic surgeon with an advanced discussion of surgical techniques applicable to OI
999 _c62137
_d62137