| 000 | 03121cam a2200301 4500500 | ||
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| 005 | 20250123102001.0 | ||
| 041 | _afre | ||
| 042 | _adc | ||
| 100 | 1 | 0 |
_aDachy, Angélique _eauthor |
| 700 | 1 | 0 |
_a Bacchetta, Justine _eauthor |
| 700 | 1 | 0 |
_a Sellier-Leclerc _eauthor |
| 700 | 1 | 0 |
_a Bertholet-Thomas, Aurélia _eauthor |
| 700 | 1 | 0 |
_a Demède, Delphine _eauthor |
| 700 | 1 | 0 |
_a Cochat, Pierre _eauthor |
| 700 | 1 | 0 |
_a Nobili, François _eauthor |
| 700 | 1 | 0 |
_a Ranchin, Bruno _eauthor |
| 245 | 0 | 0 | _aLong-term outcomes of peritoneal dialysis started in infants below 6 months of age: An experience from two tertiary centres |
| 260 | _c2020. | ||
| 500 | _a17 | ||
| 520 | _aBackground. – Little data are available for infants who started renal replacement therapy before 6 months of age. Because of extra-renal comorbidities and uncertain outcomes, whether renal replacement therapy in neonates is justified remains debatable. Methods. – We performed a retrospective analysis of all patients who began chronic peritoneal dialysis below 6 months between 2007 and 2017 in two tertiary centres. Results are presented as median (min;max). Results. – Seventeen patients (10 boys) were included (8 prenatal diagnoses, 6 premies), with the following diagnoses: congenital anomalies of kidney and urinary tract (n = 9), oxalosis (n = 5), congenital nephrotic syndrome (n = 2) and renal vein thrombosis (n = 1). Five patients had associated comorbidities. At peritoneal dialysis initiation, age was 2.6 (0.1;5.9) months, height-standard deviation score (SDS) -1.3 (-5.7;1.6) and weight-SDS -1.4 (-3.6;0.6). Peritoneal dialysis duration was 12 (2;32) months, and at peritoneal dialysis discontinuation height-SDS was -1.0 (-4.3;0.7) weight-SDS -0.7 (-3.2;0.2), parathyroid hormone 123 (44;1540) ng/L, and hemoglobin 110 (73;174) g/L. During the first 6 months of peritoneal dialysis, the median time of hospitalisation stay was 69 (15;182) days. Ten patients presented a total of 27 peritonitis episodes. Reasons for peritoneal dialysis discontinuation were switch to hemodialysis (n = 6), transplantation (n = 6), recovery of renal function (n = 2) and death (n = 1). After a follow-up of 4.3 (1.7;10.3) years, 12 patients were transplanted, 2 patients were still on peritoneal dialysis, 2 patients were dialysis free with severe chronic kidney disease and 1 patient had died. Seven patients displayed neurodevelopmental delay, of whom five needed special schooling. Conclusion. – We confirm that most infants starting peritoneal dialysis before 6 months of age will be successfully transplanted and will have a favourable growth outcome. Their quality of life will be impacted by recurrent hospitalisations and neurodevelopmental delay is frequent. | ||
| 690 | _aNeurodevelopment | ||
| 690 | _aLong-term outcomes | ||
| 690 | _aGrowth | ||
| 690 | _aInfants | ||
| 690 | _aPeritoneal dialysis | ||
| 786 | 0 | _nNéphrologie & Thérapeutique | Volume 16 | 7 | 2020-07-26 | p. 424-430 | 1769-7255 | |
| 856 | 4 | 1 | _uhttps://shs.cairn.info/revue-nephrologie-et-therapeutique-2020-7-page-424?lang=en&redirect-ssocas=7080 |
| 999 |
_c759842 _d759842 |
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