CRISPR-Cas: The bacterial immunity that supports diagnostics in virology (notice n° 234792)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01821cam a2200217 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250112063653.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mayran, Charly |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | CRISPR-Cas: The bacterial immunity that supports diagnostics in virology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2022.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 34 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | CRISPR-Cas is an adaptive immune system that enables bacteria and archaea from nucleic acid to fight invasions such as viral genomes. The ability of the CRISPR-Cas technology to effectively and precisely cleave a targeted genomic DNA region has been utilized to develop powerful genome editing tools that have been adapted for a wide range of applications, revolutionizing biological sciences. The CRISPR-Cas system consists of a Cas endonuclease triggered by an RNA guide for highly specific cleavage of targeted DNA or RNA sequences. In addition to the target-specific cleavage, some Cas enzymes, including Cas12a and Cas13a, display a collateral trans-cleavage activity that allows the cleavage of all surrounding single-stranded nucleic acids. These biosensing activities of CRISPR-Cas systems, based on target-specific binding and cleavage, are promising tools for developing accurate diagnostic methods to detect specific nucleic acids. CRISPR-Cas could therefore be used to diagnose a wide variety of diseases. In this review, we describe the more significant advances for virus detection based on CRISPR-Cas systems. |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Henry, Steven |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pinchon, Elena |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fournier-Wirth, Chantal |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cantaloube, Jean François |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Foulongne, Vincent |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Virologie | 26 | 4 | 2022-07-01 | p. 303-313 | 1267-8694 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/journal-virologie-2022-4-page-303?lang=en">https://shs.cairn.info/journal-virologie-2022-4-page-303?lang=en</a> |
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