Biomarqueurs sanguins des lésions gastriques pré-néoplasiques (notice n° 663820)
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| fixed length control field | 03464cam a2200373 4500500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250121193440.0 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | fre |
| 042 ## - AUTHENTICATION CODE | |
| Authentication code | dc |
| 100 10 - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Bazin, Thomas |
| Relator term | author |
| 245 00 - TITLE STATEMENT | |
| Title | Biomarqueurs sanguins des lésions gastriques pré-néoplasiques |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2023.<br/> |
| 500 ## - GENERAL NOTE | |
| General note | 9 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | RésuméLes lésions pré-néoplasiques gastriques (atrophie glandulaire, métaplasie intestinale, dysplasie) ne peuvent être détectées que lors d’une endoscopie œso-gastro-duodénale. En fonction de leur étendue et de leur sévérité, une surveillance est proposée, afin de détecter le plus précocement possible l’apparition d’un adénocarcinome gastrique. Lorsqu’il n’existe pas d’indication d’endoscopie, les lésions pré-néoplasiques peuvent être présentes et évoluer silencieusement. Dans les pays à bas risque de cancer gastrique comme la France, où il n’existe pas de dépistage endoscopique systématique, les patients non à haut risque d’adénocarcinome gastrique chez qui des lésions pré-néoplasiques existent ont donc une perte de chance avec un risque de développer un adénocarcinome gastrique à un stade symptomatique, de mauvais pronostic. Plusieurs biomarqueurs sériques des lésions pré-néoplasiques ont été proposés, dérivant des caractéristiques histologiques de ces lésions. Le peptide TFF3 est un biomarqueur de métaplasie intestinale, et le ratio pepsinogène I/II d’atrophie glandulaire. La place de ces biomarqueurs dans une stratégie nationale de dépistage reste à préciser. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Currently, gastric pre-neoplastic lesions (glandular atrophy, intestinal metaplasia, dysplasia) can only be detected during an upper GI endoscopy. Depending on their extent and severity, follow-up is proposed in order to detect the appearance of gastric adenocarcinoma as early as possible. When there is no indication for endoscopy, pre-neoplastic lesions may be present and evolve silently. In countries with a low risk of gastric cancer such as France, where there is no systematic endoscopic screening, patients not at high risk of gastric adenocarcinoma in whom pre-neoplastic lesions exist therefore have a loss of chance with a risk of developing gastric adenocarcinoma at a symptomatic stage, with a poor prognosis. Several serum biomarkers of pre-neoplastic lesions have been proposed, deriving from the histological characteristics of these lesions. The TFF3 peptide is a biomarker of intestinal metaplasia, and the pepsinogen I/II ratio of glandular atrophy. The place of these biomarkers in a national screening strategy remains to be clarified. |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | biopsie sérologique |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | métaplasie intestinale |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | biomarqueur |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | lésions pré-néoplasiques gastriques |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | atrophie glandulaire |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | pepsinogène |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | TFF3 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | gastric pre-neoplastic lesions |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | glandular atrophy |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | intestinal metaplasia |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | biomarker |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | pepsinogen |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | serological biopsy |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
| Topical term or geographic name as entry element | TFF3 |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nozeret, Karine |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Touati, Eliette |
| Relator term | author |
| 700 10 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lamarque, Dominique |
| Relator term | author |
| 786 0# - DATA SOURCE ENTRY | |
| Note | Hépato-Gastro & Oncologie Digestive | 30 | 1 | 2023-01-01 | p. 47-53 | 2115-3310 |
| 856 41 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://shs.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2023-1-page-47?lang=fr&redirect-ssocas=7080">https://shs.cairn.info/revue-hepato-gastro-et-oncologie-digestive-2023-1-page-47?lang=fr&redirect-ssocas=7080</a> |
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