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Ophiocordyceps sinensis, also called cordyceps, is part of traditional Chinese and Tibetan pharmacopoeias. This medicinal fungus native to the high Himalaya Mountains is used as a tonic and an aphrodisiac. As it spread all over the world, its production processes, pharmaceutical forms, and indications have multiplied. From AIDS to cancer and diabetes, it has become a true panacea for the pharmacopoeia of alternative and complementary medicines. Locally, cordyceps has become the main business in an economy that is reshaping Tibetan society. An outline of the biography of cordyceps proposes a multilocation anthropological approach. This biography includes material and symbolic features and specifically examines the validation process that combines “traditional” and “modern” allegations, references to nature, and scientific validation.